Michele grew up in Buffalo, New York and Johnson City, Tennessee. During and after graduating college she worked at the local Buffalo television station in camera and lighting on news and public access shows. She moved to Los Angeles and carved out a career in commercial production, climbing up from production assistant to producing to finally directing and writing.
In 2013 Shoot Magazine chose her for the director’s showcase for up and coming directors to watch. In 2016 she won the Academy of Motion Picture Nicholl Fellowship for her feature screenplay Talking About The Sky. She completed a screenplay adaptation for One Night In Mississippi for award winning Caviar Films, which made the 2018 Blacklist. Her short film Sweet Mercy opened at the Savannah International Film Festival November, 2018.